Indica vs Sativa for PTSD: Effects Explained | CAC
Skip to content

Is indica or sativa better for PTSD? A guide to choosing the right strain

Top Rated Cannabis Clinics

1
User Rating
Rated 5.0 out of 5
5.0
Visit Website Read reviews
2
User Rating
Rated 3.4 out of 5
3.4
Visit Website Read reviews
3
User Rating
Rated 3.4 out of 5
3.4
Visit Website Read reviews

In the wake of a traumatic event, around 20% of us will experience post-traumatic stress disorder (PTSD).

Statistics show that PTSD affects 1 in 5 of us who have experienced trauma, equating to around 10% of the overall UK population. This condition is often characterised by states of extreme anxiety, flashbacks, and nightmares – as well as a raft of physical symptoms and other unfavourable health outcomes, including social withdrawal and depression.   

There is, as we will explore shortly, a sizeable body of evidence to suggest that medical cannabis for PTSD may aid trauma survivors on the path to healing via other therapies, such as counselling and cognitive behavioural therapy (CBT)

However, with so many different strains to choose from, those who are new to medicinal cannabis may struggle to identify the right strains for their needs and symptoms. 

Key Takeaways

  • Indica and Sativa strains have different appearances, chemical compositions and potential effects.
  • Indica strains tend to be more sedative, while Sativa strains can provide energy and focus.
  • The right strain for an individual’s PTSD symptoms may vary, and it is important to find the best match through experimentation with different strains.
  • It is important to consult with a medical professional before choosing a medicinal marijuana strain for treating PTSD.

The Symptoms Of PTSD And How Cannabis Therapy May Help

Every individual’s experience with PTSD is unique. The scope and severity of symptoms may vary from one person to the next, as can the timeframe in which people experience these symptoms.

However, the NHS website outlines a number of common symptoms experienced, to varying degrees, by those with PTSD. These include:

  • Intrusive and upsetting thoughts and images
  • Reliving traumatic events through flashbacks and nightmares
  • Hyperarousal, irritability and mood swings
  • Insomnia and troubled sleep
  • Difficulty concentrating
  • Social withdrawal
  • Self-harm or self-destructive behaviours
  • Physical symptoms such as trembling, nausea, headaches or chest pains

Like many anxiety disorders, PTSD is often accompanied by bouts of serious depression. A 2015 US study asserts that around half of all people affected by PTSD also experience severe depression. 

How Can Medicinal Cannabis Help Relieve Symptoms Of PTSD?

While the symptoms of PTSD are wide-ranging, they broadly stem from anxiety and depression. Studies have shown that the body’s endocannabinoid system plays a significant role in regulating mood and sleep, as well as other key bodily functions such as reproductive and immune functions.

The cannabis plant is full of compounds called cannabinoids such as cannabidiol (CBD), tetrahydrocannabinol (THC) and cannabigerol (CBG) which studies have shownThe cannabis plant is full of compounds called cannabinoids, such as cannabidiol (CBD), tetrahydrocannabinol (THC) and cannabigerol (CBG), which studies have shown to interact with the body’s endocannabinoid system to create positive health outcomes. 

Weed plants also contains a wide range of terpenes. In addition to giving the plant its distinctive taste and smell, these terpenes can also increase the efficacy of cannabinoids by creating an ‘entourage effect’ that can help mitigate entourage effectunwanted side effects. 

Multiple studies have demonstrated a link between medicinal cannabis use and a significant abatement of PTSD symptoms in the majority of participants. 

Indica vs Sativa: How do they compare for PTSD symptoms?

Symptom / Goal Indica-Dominant Strains Sativa-Dominant Strains
Sleep and nightmares Often more calming and sedative. May support deeper rest and reduced sleep disruption Can be stimulating or mentally active. Not typically suited for evening or night use
Anxiety and hyperarousal May help reduce physical tension and hypervigilance, especially with calming terpenes Can increase alertness but may exacerbate anxiety in THC-sensitive individuals
Mood and energy May stabilise mood or provide grounding during emotional distress Often experienced as uplifting or energising. May support low-motivation states
Focus and concentration Can support relaxation but may reduce cognitive sharpness in some users Sometimes used for mental clarity or creative focus, depending on THC/terpene balance
Appetite support Frequently associated with appetite stimulation May increase appetite depending on individual response and terpene mix
Physical pain or tension Commonly used for body-based discomfort such as muscle tightness or headaches Some users report relief from neuropathic or tension-related symptoms
Typical THC/CBD profile Often high in THC. CBD content varies and is cultivar-specific Also often high in THC. Some sativa-dominant strains now include elevated CBD
Common terpene profile Myrcene, beta-caryophyllene, linalool, limonene Limonene, terpinolene, pinene, caryophyllene, ocimene

Note: Most modern strains are hybrids with indica or sativa-leaning effects, rather than genetically pure types. 

Cannabinoid and terpene content varies widely, and both THC and CBD-dominant options are available in either category. 

As research advances, clinicians are shifting away from classifying strains strictly as indica or sativa and instead focusing on their specific chemical profiles. Always consult a medical cannabis specialist before starting or adjusting treatment.

Is Indica Or Sativa Better For PTSD?

That’s a tricky question to answer. As countries around the world shed the stigma of medicinal cannabis use, we gain a greater scientific understanding of the effects of cannabinoids and terpenes on our bodies. This science-based approach gives rise to the purposeful breeding of cannabis plants to produce strains with predetermined medicinal effects.

Therefore, it’s easier for individuals to experiment with different strains (be they Indica, Sativa or hybrid) and make informed decisions as to which is best for their symptoms. 

With that in mind, let’s take a look at the properties of indica and sativa strains to get to know their characteristics and potential effects a little better. 

Properties Of Indica Cannabis Strains

Indica and Indica-dominant strains generally contain higher concentrations of CBD as well as terpenes such as myrcene, linalool, limonene, humulene and beta-caryophyllene.

As such, these strains tend to have a subtly sedative effect and may also stimulate appetite in those with trauma-related undereating disorders. Some (but not all) indica strains have a low THC content, giving them very mild (if any) intoxicating effects, making them a good fit for busy professionals. That said, there are some indica strains that have high concentrations of both CBD and THC, which can result in ‘couch lock’.

Indica-dominant UK medical weed strains for PTSD 

Often chosen for sleep, calming anxiety, muscle tension, and evening use.

Cultivar Name Potential Uses for PTSD Dominant Terpenes THC/CBD Ratio Brand
Donkey Butter (DBT T24) Nighttime use for tension and sleep Myrcene, α-pinene, β-pinene 24% / <1% 4C Labs
Wedding Cake (WC T22) May reduce anxiety and improve relaxation Myrcene, caryophyllene, α-pinene 22% / <1% Glass Pharms
Kush Mints (KM T24) Evening strain for worry and muscle tension Limonene, caryophyllene, linalool 24% / <1% Glass Pharms
Strawberry Cake (SCK-S T22) Can support stress relief and sleep Myrcene, β-pinene, α-pinene 22% / <1% 4C Labs
Cold Creek Kush (CCK-S T25) Often used for sleep and physical tension Myrcene, limonene, α-pinene 25% / <1% 4C Labs
Glitter Bomb (GB T21) May be calming for anxiety without full sedation Myrcene, linalool, caryophyllene 21% / <1% Glass Pharms
Black Cookies (BC T23) Can reduce overstimulation and help sleep onset Myrcene, α-pinene, caryophyllene 23% / <1% Oceanic Relief
Lavender Cake (LCE T20) Commonly selected for calming effects Myrcene, caryophyllene, α-pinene 20% / <1% Terra Verde
Black Cherry Punch (BCP T15) Mild option for anxiety or first-time patients Myrcene, limonene, caryophyllene 15% / <1% SatiCanna
Fire Cookies (FC Smalls T24) Potential to aid with anxiety and emotional stress Myrcene, limonene, caryophyllene 24% / <1% Medicus

Properties Of Sativa Weed Strains

Sativa and Sativa-dominant strains tend to have higher concentrations of THC. As such, those who are new to medicinal cannabis use or who experience pronounced anxiety may benefit from a hybrid strain that mitigates the potential side effects of THC. 

Sativa strains generally have a more intoxicating effect, inducing a sense of calm or even euphoria. However, there are some strains like harlequin which have very low levels of THC and virtually no intoxicating effects. Some strains can also enhance concentration and creativity. Studies show that many of the terpenes in Sativa weed strains have analgesic properties, making them well suited to relieving painful physical symptoms of PTSD like headaches or chest and stomach pain.  

Sativa-dominant UK medical weed strains for PTSD

Often selected for focus, mood elevation, and daytime anxiety relief.

Cultivar Name Potential Uses for PTSD Dominant Terpenes THC/CBD Ratio Brand
Tangerine Boost (TB T20) May help with focus, daytime anxiety relief Limonene, myrcene, caryophyllene 20% / <1% Glass Pharms
Alaskan Thunder (ATD T29) Energising for low motivation or mental fatigue Limonene, α-pinene, β-pinene 29% / <1% 4C Labs
Moby Dick (MDK T21) Energising strain for daytime low motivation Limonene, myrcene, caryophyllene 21% / <1% 4C Labs
MAC Doughnut (MDO T27) May promote relaxation without sedation Limonene, caryophyllene, linalool 27% / <1% All Nations
StöLö Haze (SH T26) Some use it for mood balance and mental clarity Myrcene, caryophyllene, α-pinene 26% / <1% All Nations
Blackberry Sour (BS T19) May ease nightmares and help with evening relaxation Myrcene, limonene, caryophyllene 19% / <1% Glass Pharms
GMO Tropical Reign (GMO-TR T29) May assist with low mood and irritability Caryophyllene, limonene, myrcene 29% / <1% 4C Labs
Heavy Gas Hitter (HGH T28) May assist with intrusive thoughts and irritability Myrcene, limonene, β-pinene 28% / <1% BC Green
First Class Funk (FCF T22) Used for emotional rebalancing and tension Limonene, caryophyllene, myrcene 22% / <1% Glass Pharms
High Silver (HSR T17–20) Could assist with focus and emotional clarity Myrcene, caryophyllene, humulene 17–20% / <1% Find

Should I Choose Indica Or Sativa For PTSD?

Broadly speaking, Indica-dominant strains are most commonly used to aid anxiety disorders such as PTSD. However, the right strain for you depends entirely on your individual experience with PTSD and the ways in which your symptoms impede your everyday life.

Some, for instance, find themselves unable to concentrate and focus at work or hobbled by a depression which saps them of their energy. These people may benefit from a sativa-dominant strain like Blue Dream or a hybrid strain like ACDC. These can help to energise the mind and restore cognitive function.

On the other hand, those who find themselves in frequent states of hyperarousal or who find it difficult to sleep may benefit more from an indica or indica-dominant strain like LA Confidential or Lavender Kush. 

medical cannabinoids uk guide

FAQs

Can cannabis worsen PTSD symptoms?

While there is ongoing research on the effects of cannabis on PTSD symptoms, anecdotal evidence suggests that many individuals with PTSD have found relief from their symptoms through the use of medicinal marijuana.

With that said, yes, high THC strains can potentially exacerbate anxiety and panic attacks in certain individuals. This is why it’s important to work with a specialist doctor when choosing the right strains and research before trying new strains.

What’s the best way to take medical cannabis for PTSD?

There is no one-size-fits-all approach, but the way you take medical cannabis can affect how quickly it works and how long the effects last.

  • Vaping flower allows for fast onset, often within minutes. This can be helpful for managing sudden symptoms such as anxiety spikes or flashbacks. Some patients find it useful during high-stress moments or in the evenings before bed.
  • THC vapes are also fast-acting and more discreet. They are commonly used for breakthrough symptoms or as part of a portable daytime option. 
  • Cannabis oil tends to take longer to work, but the effects can last several hours. This makes it a good option for ongoing symptom relief, especially for sleep, mood, or appetite support.

Most patients use a combination of options. Your clinician can help tailor a treatment plan based on your symptoms, lifestyle, and response to different formats.

What is the difference between Indica and Sativa?

Morphologically, Sativa plants are taller and have thinner leaves than Indica plants. In terms of chemical composition, Sativas tend to have higher levels of THC while Indicas have higher levels of CBD. However, these differences are not always absolute, as many strains now contain a combination of both cannabinoids.

Are there any risks associated with using medicinal marijuana for PTSD?

As with any medication, there are potential risks associated with using medicinal cannabis for PTSD. These may include interactions with other medications or pre-existing health conditions. Working with a trusted doctor and starting with low doses is important to determine the best treatment plan for your individual needs.

Is Indica or Sativa better for anxiety related to PTSD?

Both Indica and Sativa-dominant strains can offer relief from anxiety symptoms, but they do so in different ways.

  • Indica-leaning strains are often preferred by patients who experience physical symptoms of anxiety, such as racing heart, restlessness or insomnia. These cultivars tend to be calming and body-focused, which can help reduce tension and overstimulation.
  • Sativa-leaning strains may suit patients whose anxiety presents as low mood, mental fog, or daytime fatigue. When carefully dosed, they may improve focus and lift emotional flatness — but too much THC in a Sativa can also trigger racing thoughts or discomfort in some people.

If anxiety is your primary concern, strains high in myrcene, linalool, or caryophyllene may offer the most reliable support. Your prescribing clinician can tailor a treatment plan based on your symptom profile and past experience with cannabis.

Is Indica or Sativa better for sleep?

Sleep issues are one of the most common reasons PTSD patients seek medical cannabis.

  • Indica-dominant cultivars are typically favoured for sleep support, especially if insomnia is linked to nightmares, muscle tension or anxiety at bedtime. Many of these strains are rich in myrcene or linalool, two terpenes associated with sedation and calm.
  • Sativa-dominant strains are less commonly used for sleep. However, some patients with ADHD, depression or early-night restlessness may benefit from a carefully chosen Sativa earlier in the evening to wind down before transitioning to an Indica for sleep.

Cannabis affects everyone differently, and THC can disrupt sleep if not dosed correctly. A personalised prescription that includes the right format (inhaled, oil, or both) and timing is key to supporting healthy sleep. Keep in mind that the effects of one strain can differ person to person, so a little trial and error may be needed. 

Conclusion

While there are some obvious risks associated with using medicinal cannabis for PTSD, there is also a growing body of evidence to suggest that it can be an effective treatment option for many individuals.

Whether you choose an Indica-dominant, Sativa-dominant or hybrid strain depends entirely on your individual experience and symptoms of PTSD. Always consult with a medical professional and thoroughly research before trying new strains.

Looking for the best UK medical cannabis clinic for your needs?

You’ve come to the right place here at Cannabis Access Clinics. You’ll find detailed reviews of the top UK medical cannabis clinics to help you make the most informed decision about your care.

Author
Kristof
Kristof is the head of content here at CAC, and has been instrumental in shaping the voice and tone of our brand. With his years of experience in content strategy and creation, combined with a Master's degree in English, Kristof brings a wealth of knowledge and expertise to our team. Kristof's role at CAC goes beyond just creating content - he also oversees the entire content strategy for the company. This means that every blog post, social media update, and email campaign is carefully planned and executed under his guidance. A prescribed medical cannabis patient and avid CBD advocate, Kristof is deeply passionate about educating the public about the benefits of alternative medicine.

Pro Copywriters Profile